Detalhe da pesquisa
1.
Targeting JMJD1C to selectively disrupt tumor Treg cell fitness enhances antitumor immunity.
Nat Immunol
; 25(3): 525-536, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38356061
2.
Cytoplasmic DNA sensing by KU complex in aged CD4+ T cell potentiates T cell activation and aging-related autoimmune inflammation.
Immunity
; 54(4): 632-647.e9, 2021 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33667382
3.
TG468: a text graph convolutional network for predicting clinical response to immune checkpoint inhibitor therapy.
Brief Bioinform
; 25(2)2024 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38390990
4.
SNX10-mediated LPS sensing causes intestinal barrier dysfunction via a caspase-5-dependent signaling cascade.
EMBO J
; 40(24): e108080, 2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34747049
5.
KinomeMETA: meta-learning enhanced kinome-wide polypharmacology profiling.
Brief Bioinform
; 25(1)2023 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38113075
6.
Goliath induces inflammation in obese mice by linking fatty acid ß-oxidation to glycolysis.
EMBO Rep
; 24(4): e56932, 2023 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36862324
7.
RNAincoder: a deep learning-based encoder for RNA and RNA-associated interaction.
Nucleic Acids Res
; 51(W1): W509-W519, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37166951
8.
A task-specific encoding algorithm for RNAs and RNA-associated interactions based on convolutional autoencoder.
Nucleic Acids Res
; 51(21): e110, 2023 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37889083
9.
The emergence of machine learning force fields in drug design.
Med Res Rev
; 44(3): 1147-1182, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38173298
10.
An inductive graph neural network model for compound-protein interaction prediction based on a homogeneous graph.
Brief Bioinform
; 23(3)2022 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35275993
11.
Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido[2,3-d]pyrimidin-7-one-based SOS1 inhibitor.
Bioorg Med Chem Lett
; 107: 129780, 2024 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38714262
12.
Modifiable and Non-Modifiable Risk Factors for Premature Coronary Heart Disease (PCHD): Systematic Review and Meta-Analysis.
Heart Lung Circ
; 33(3): 265-280, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38365496
13.
Multi-instance learning of graph neural networks for aqueous pKa prediction.
Bioinformatics
; 38(3): 792-798, 2022 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34643666
14.
Do patients with prediabetes managed with metformin achieve better glycaemic control? A national study using primary care medical records.
Diabet Med
; 40(9): e15170, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37381113
15.
Discovery and identification of a novel small molecule BCL-2 inhibitor that binds to the BH4 domain.
Acta Pharmacol Sin
; 44(2): 475-485, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35918411
16.
143D, a novel selective KRASG12C inhibitor exhibits potent antitumor activity in preclinical models.
Acta Pharmacol Sin
; 44(7): 1475-1486, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-36725884
17.
Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease.
Acta Pharmacol Sin
; 44(4): 791-800, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36229599
18.
DrugSpaceX: a large screenable and synthetically tractable database extending drug space.
Nucleic Acids Res
; 49(D1): D1170-D1178, 2021 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33104791
19.
Experience of clinical nurses engaged in caring for patients with COVID-19: A qualitative systematic review and meta-synthesis.
J Clin Nurs
; 32(15-16): 5258-5273, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-36639947
20.
Risk Factors for Early-Onset Versus Late-Onset Coronary Heart Disease (CHD): Systematic Review and Meta-Analysis.
Heart Lung Circ
; 32(11): 1277-1311, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37777398